Jab to reduce cholesterol to help prevent heart disease

 Jab to reduce cholesterol to help prevent heart disease

Jab To reduce cholesterol to help prevent heart disease

 Jab to reduce cholesterol to help prevent heart disease

Human trials of a cholesterol-lowering vaccine to help prevent heart disease are ongoing after successful studies in mice.

Researchers at the Medical University of Vienna test the safety of its experimental treatment in 72 volunteers.

The Joint Appeals Board is designed to prevent clogging of the arteries of fat deposits.

Offer patients an alternative to taking pills every day to reduce your risk of stroke, angina pectoris and heart attacks.

The reinforcement jab

Dr. Guenther Staffler and his colleagues at the Organization for Applied Scientific Research in the Netherlands in the European Heart Journal, it takes years of testing to see if the treatment is safe enough and effective for human use.

Even if it is available, within six years, should not be considered an excuse for people to exercise and eat a lot of meals avoid fat, they add.

The jab helps the immune system to attack the body of a protein called PCSK9, which otherwise allow low-density lipoprotein (LDL) cholesterol to accumulate in the blood.

Researchers predict that patients could have an annual booster to recharge your immunity.

In mice, the treatment reduces LDL cholesterol by 50% for 12 months and appears to protect against the accumulation of fatty deposits in the arteries (atherosclerosis).

What is cholesterol?

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?What is Cholesterol

Cholesterol is a fatty substance in the blood. We all need, but too much "bad" LDL cholesterol increases the risk of cardiovascular disease.

The "good" cholesterol, high density lipoprotein (HDL), on the other hand, is beneficial because it helps carry other types of blood cholesterol to the liver where it can decompose.

Some people have high cholesterol due to a hereditary disease called familial hypercholesterolemia.

Poor nutrition, high alcohol consumption, smoking and inactivity are also linked to high cholesterol.

Are there any pills to reduce it?

People with high cholesterol can take cholesterol lowering, called statins, in order to reduce their risk of cardiovascular disease.

But even if they are very cheap and effective, they do not work for everyone.

Some people do not like to take medicine every day or forget to take it because they feel good. Rarely, there may be side effects.

Researchers looked for treatment options that can give patients or instead statins.

What will happen from afar?

The vaccine induces immunity against a protein produced by the body, rather than something foreign

The first phase of testing with 72 human volunteers is due to be completed by the end of the year.

This will help to check for safety problems or side effects before starting further studies in people.

There is concern that the therapeutic vaccine may increase the risk of diabetes.

Researchers from the Medical University of Vienna who are pursuing studies in humans will be in sight for this.

Dr. Tim Chico, a cardiologist at Sheffield University, said, "There are many questions as to whether this approach could work in humans.

"This is further evidence that causes heart disease and lower cholesterol reduces the risk of heart disease, thus confirming the importance of a healthy lifestyle for all and drugs such as statins for some people reduce risk Heart disease ".

Prof Nilesh Samani Sir, from the British Heart Foundation, said: "Finding new ways to control people's cholesterol is absolutely vital.

"Although only tested in mice, this vaccine could lead to a simple way to get high cholesterol and ultimately reduce the risk of people with heart disease."