15 Symptoms and signs of rheumatoid arthritis (RA)
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| Symptoms and signs of rheumatiod arthritis RA |
15 Symptoms and signs of rheumatoid arthritis (RA)
Although the early symptoms of rheumatoid arthritis can be mimicked by other diseases, the symptoms are very characteristic of rheumatoid disease. Symptoms and signs of rheumatoid arthritis include:
- tired
- Joint pain
- Common tenderness
- Inflammation of the joints
- Joint redness
- Heat Seals
- Joint stiffness
- Loss of joint amplitude
- lameness
- Joint deformity
- Many affected joints (Polyarthritis)
- The two parts of the body concerned (symmetric)
- Loss of joint function
- anemia
- fever
Symptoms and signs of rheumatoid arthritis (RA)
- Rheumatoid arthritis is a chronic inflammation that causes joints and other parts of the body's autoimmune disease.
- Symptoms and signs of rheumatoid arthritis include:
- Joint pain, and joints of the feet, hands and knees,
- Inflammation of the joints,
- fever,
- lameness
- polyarthritis,
- The loss of amplitude of motion,
- Soft joints,
- The loss of joint function,
- Joint stiffness,
- tired,
- Articular redness,
- Rheumatoid nodules,
- anemia,
- Heat seals,
- Joint deformity and
- Symptoms and signs affecting both sides of the body (symmetry).
- Rheumatoid arthritis is a chronic disease characterized by periods of remission and disease eruption.
- In rheumatoid arthritis, multiple joints are usually, but not always, affected in a symmetrical pattern.
- Chronic inflammation of rheumatoid arthritis can cause permanent deformation and destruction of the joints.
- Joint damage can occur quickly and does not always match the severity of the symptoms of rheumatoid arthritis.
- "Rheumatoid Factor" is an antibody that can be found in the blood of 80% of people with rheumatoid arthritis. Rheumatoid factor is detected in a single blood test. Risk factors for the development of rheumatoid arthritis include genetics, smoking, silica inhalation, periodontal disease and microbes in the intestine (intestinal bacteria).
- There is no cure for rheumatoid arthritis. The treatment of rheumatoid arthritis involves an optimal combination of patient education, rest and exercise, protection of joints, medications, and sometimes surgery.
- Drugs used in the treatment of rheumatoid arthritis include NSAIDs, DMARDs, TNF alpha inhibitors, IL-6 inhibitors, T-cell activation inhibitors, depleting B cells, JAK, immunosuppressants and steroids.
- Early treatment of rheumatoid arthritis results in a better prognosis.
- Rheumatoid arthritis can affect people of all ages. The cause of rheumatoid arthritis is unknown.
What is rheumatoid arthritis (RA)?
Definition of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammation causing autoimmune disease of the joints. Autoimmune diseases are diseases that occur when the body tissues are mistakenly attacked by their own immune system. The immune system contains a complex organization of cells and antibodies designed to "look and destroy" the body's invaders, especially infections. Patients with autoimmune diseases have antibodies and immune cells in the blood that target their own tissues of the body, which can be associated with inflammation. Although inflammation of the tissues around joints and inflammatory arthritis are characteristic of rheumatoid arthritis, the disease can cause inflammation and damage to other organs of the body.
Because it can affect many other organs of the body, rheumatoid arthritis is known as a systemic disease and is sometimes called rheumatoid disease.
Rheumatoid arthritis is a classical rheumatic disease. Rheumatoid arthritis begins in people younger than 16 years old is known as juvenile idiopathic arthritis or JIA (formerly juvenile rheumatoid arthritis or JRA).
Osteoarthritis for rheumatoid arthritis
Rheumatoid arthritis is a destructive joint disease that is caused by inflammation in tissue that normally produces a lubricating fluid for joints. When this tissue remains inflamed, which leads to a deformation to loosen the ligaments of the joint and destroy the eroded joints of cartilage and bone.
Osteoarthritis is a non-inflammatory joint disease by the articular cartilage, typically asymmetrically, so that only a knee or hand can be affected. Previous page illustration shows the difference between a normal joint and osteoarthritis and rheumatoid arthritis.
Although rheumatoid arthritis is a chronic disease, meaning it can last for years, patients can experience long periods without symptoms. However, rheumatoid arthritis is
Progressive has the potential to cause significant joint destruction and functional disability.
A joint is where two bones allow movement of the body parts. Arthritis means inflammation of the joints. Articular inflammation of rheumatoid arthritis causes swelling, pain, stiffness and redness in the joints. Inflammation of rheumatoid disease can also occur in the tissues around the joints, such as tendons, ligaments and muscles.
In some people with rheumatoid arthritis, chronic inflammation leads to destruction of the cartilage, bones and ligaments, causing deformity of the joints. Joint lesions can occur at the onset of the disease and be progressive. In addition, studies have shown that progressive joint damage does not necessarily correspond with the degree of pain, stiffness and swelling present in the joints.
Rheumatoid arthritis is a common rheumatic disease, affecting approximately 1.3 million people in the United States, according to current census data. The disease is three times more common in women than in men. It affects people of all races as well. The disease can start at any age and even affects children (juvenile idiopathic arthritis), but often begins after 40 years and before 60 years. Although rare, in some families, several members may be affected, suggesting a genetic basis for the disease.
What are the causes of rheumatoid arthritis and risk factors?
The cause of rheumatoid arthritis is unknown. Although infectious agents such as viruses, bacteria and fungi have long been suspected, none has been proven to cause it. The cause of rheumatoid arthritis is a very active area of research worldwide. It is believed that the tendency to develop rheumatoid arthritis may be genetically inherited (hereditary). They identified certain genes that increase the risk of rheumatoid arthritis. It is also suspected that certain infections or factors in the environment can trigger activation of the immune system in sensitive individuals. This evil-oriented immune system attacks the body's own tissues. This leads to inflammation in the joints and sometimes in various organs of the body such as the lungs or the eyes.
It is not known what triggers the onset of rheumatoid arthritis. Whatever the exact trigger, the result is an immune system that is oriented to promote inflammation in the joints and sometimes other tissues in the body. Immune cells called lymphocytes,
(Cytokines such as tumor factor / necrosis TNF, interleukin-1 / IL-1 and interleukin-6 / IL-6) are expressed in inflamed areas.
Intestinal bacteria, smoking and gum disease
Environmental factors also appear to play a role in the development of rheumatoid arthritis. For example, scientists have reported that smoking tobacco, exposure to mineral silica and chronic periodontal disease increase the risk of developing rheumatoid arthritis. There are different theories on intestinal bacteria (microbiome intestinal microbes that naturally live in the intestinal mucosa) that can trigger the onset of rheumatoid arthritis in genetically predisposed individuals. No specific microbes have been identified as defined causes.
What are the complications of rheumatoid arthritis?
Since rheumatoid arthritis is a systemic disease, inflammation can affect their organs and parts of the body other than the joints. Inflammation of the glands of the eyes and mouth can cause drying of these areas and is known as Sjögren's syndrome. Dry eyes can lead to abrasion of the cornea.
Inflammation of the whites of the eyes (sclera) is known as scleritis and can be very dangerous to the eye. Rheumatoid inflammation of the lung mucosa (pleurisy) causes chest pain with deep breathing, shortness of breath or cough. Pulmonary tissue can also swell and sometimes scarring and nodules of inflammation (rheumatoid nodules) develop in the lungs.
The inflammation of the tissue (pericardium) surrounding the heart, called pericarditis, can cause chest pain usually changes the intensity in the prone position or lean. Rheumatoid arthritis is associated with an increased risk of heart attack. Rheumatoid disease can reduce the number of red blood cells (anemia) and white blood cells. Reduction in the number of white blood cells may be associated with enlarged spleen (called Felty's syndrome) and may increase the risk of infections. The risk of cancer of the lymph gland (lymphoma) is higher in patients with rheumatoid arthritis, especially those who have sustained active joint inflammation. They can produce strong bulges or bumps under firm skin (subcutaneous nodules called rheumatoid nodules) around elbows and fingers where frequent pressure. , Sometimes even if these nodules do not usually cause symptoms, they may be infected. The nerves can be pinched in the wrists to cause carpal tunnel syndrome. A rare and serious complication, most often with long-standing rheumatoid disease, is inflammation of the blood vessels (vasculitis). Vasculitis can harm the blood supply to the tissues and cause tissue death (necrosis). This is most often first visible tiny black areas around the nail beds or leg ulcers.
What are the signs and symptoms of rheumatoid arthritis?
AR symptoms come and go, depending on the degree of inflammation of the tissues. When the body tissues are inflamed, the disease is active. When tissue inflammation decreases, the disease is inactive (in remission). Remissions may occur spontaneously or with treatment and may last for weeks, months or years. During remissions, the symptoms of the illness disappear, and people generally feel good. When the disease becomes active again (relapse), the symptoms reappear. The return of disease activity and symptoms is called a flare. The course of rheumatoid arthritis varies among people affected, and the periods of flares and remissions are typical.
How do you feel about rheumatoid arthritis?
When the disease is active, symptoms of rheumatoid arthritis may include
Muscle and joint stiffness is usually more visible in the morning and after periods of inactivity. This is known as morning stiffness and post-sedentary rigidity. Arthritis is common during the outbreaks of the disease. Also during eruptions, the joints often become hot, red, swollen, painful and tender. This occurs because the tissue lining of the joint (synovial) becomes inflamed, leading to excessive production of joint fluid (synovial fluid). Synovial also thickens with inflammation (synovitis).
Osteoarthritis for rheumatoid arthritis
 |
| rheumatoid arthritis |
Rheumatoid arthritis is a destructive joint disease that is caused by inflammation in tissue that normally produces a lubricating fluid for joints. When this tissue remains inflamed, which leads to a deformation to loosen the ligaments of the joint and destroy the eroded joints of cartilage and bone.
Osteoarthritis is a non-inflammatory joint disease by the articular cartilage, typically asymmetrically, so that only a knee or hand can be affected. Previous page illustration shows the difference between a normal joint and osteoarthritis and rheumatoid arthritis.
Although rheumatoid arthritis is a chronic disease, meaning it can last for years, patients can experience long periods without symptoms. However, rheumatoid arthritis is
Progressive has the potential to cause significant joint destruction and functional disability.
A joint is where two bones allow movement of the body parts. Arthritis means inflammation of the joints. Articular inflammation of rheumatoid arthritis causes swelling, pain, stiffness and redness in the joints. Inflammation of rheumatoid disease can also occur in the tissues around the joints, such as tendons, ligaments and muscles.
In some people with rheumatoid arthritis, chronic inflammation leads to destruction of the cartilage, bones and ligaments, causing deformity of the joints. Joint lesions can occur at the onset of the disease and be progressive. In addition, studies have shown that progressive joint damage does not necessarily correspond with the degree of pain, stiffness and swelling present in the joints.
Rheumatoid arthritis is a common rheumatic disease, affecting approximately 1.3 million people in the United States, according to current census data. The disease is three times more common in women than in men. It affects people of all races as well. The disease can start at any age and even affects children (juvenile idiopathic arthritis), but often begins after 40 years and before 60 years. Although rare, in some families, several members may be affected, suggesting a genetic basis for the disease.
What are the causes of rheumatoid arthritis and risk factors?
The cause of rheumatoid arthritis is unknown. Although infectious agents such as viruses, bacteria and fungi have long been suspected, none has been proven to cause it. The cause of rheumatoid arthritis is a very active area of research worldwide. It is believed that the tendency to develop rheumatoid arthritis may be genetically inherited (hereditary). They identified certain genes that increase the risk of rheumatoid arthritis. It is also suspected that certain infections or factors in the environment can trigger activation of the immune system in sensitive individuals. This evil-oriented immune system attacks the body's own tissues. This leads to inflammation in the joints and sometimes in various organs of the body such as the lungs or the eyes.
It is not known what triggers the onset of rheumatoid arthritis. Whatever the exact trigger, the result is an immune system that is oriented to promote inflammation in the joints and sometimes other tissues in the body. Immune cells called lymphocytes,
(Cytokines such as tumor factor / necrosis TNF, interleukin-1 / IL-1 and interleukin-6 / IL-6) are expressed in inflamed areas.
Intestinal bacteria, smoking and gum disease
Environmental factors also appear to play a role in the development of rheumatoid arthritis. For example, scientists have reported that smoking tobacco, exposure to mineral silica and chronic periodontal disease increase the risk of developing rheumatoid arthritis. There are different theories on intestinal bacteria (microbiome intestinal microbes that naturally live in the intestinal mucosa) that can trigger the onset of rheumatoid arthritis in genetically predisposed individuals. No specific microbes have been identified as defined causes.
What are the complications of rheumatoid arthritis?
Since rheumatoid arthritis is a systemic disease, inflammation can affect their organs and parts of the body other than the joints. Inflammation of the glands of the eyes and mouth can cause drying of these areas and is known as Sjögren's syndrome. Dry eyes can lead to abrasion of the cornea.
Inflammation of the whites of the eyes (sclera) is known as scleritis and can be very dangerous to the eye. Rheumatoid inflammation of the lung mucosa (pleurisy) causes chest pain with deep breathing, shortness of breath or cough. Pulmonary tissue can also swell and sometimes scarring and nodules of inflammation (rheumatoid nodules) develop in the lungs.
The inflammation of the tissue (pericardium) surrounding the heart, called pericarditis, can cause chest pain usually changes the intensity in the prone position or lean. Rheumatoid arthritis is associated with an increased risk of heart attack. Rheumatoid disease can reduce the number of red blood cells (anemia) and white blood cells. Reduction in the number of white blood cells may be associated with enlarged spleen (called Felty's syndrome) and may increase the risk of infections. The risk of cancer of the lymph gland (lymphoma) is higher in patients with rheumatoid arthritis, especially those who have sustained active joint inflammation. They can produce strong bulges or bumps under firm skin (subcutaneous nodules called rheumatoid nodules) around elbows and fingers where frequent pressure. , Sometimes even if these nodules do not usually cause symptoms, they may be infected. The nerves can be pinched in the wrists to cause carpal tunnel syndrome. A rare and serious complication, most often with long-standing rheumatoid disease, is inflammation of the blood vessels (vasculitis). Vasculitis can harm the blood supply to the tissues and cause tissue death (necrosis). This is most often first visible tiny black areas around the nail beds or leg ulcers.
What are the signs and symptoms of rheumatoid arthritis?
AR symptoms come and go, depending on the degree of inflammation of the tissues. When the body tissues are inflamed, the disease is active. When tissue inflammation decreases, the disease is inactive (in remission). Remissions may occur spontaneously or with treatment and may last for weeks, months or years. During remissions, the symptoms of the illness disappear, and people generally feel good. When the disease becomes active again (relapse), the symptoms reappear. The return of disease activity and symptoms is called a flare. The course of rheumatoid arthritis varies among people affected, and the periods of flares and remissions are typical.
How do you feel about rheumatoid arthritis?
When the disease is active, symptoms of rheumatoid arthritis may include
- tired,
- Loss of energy,
- lack of appetite,
- Low fever,
- Muscle and joint pain, and
- rigidity.
Muscle and joint stiffness is usually more visible in the morning and after periods of inactivity. This is known as morning stiffness and post-sedentary rigidity. Arthritis is common during the outbreaks of the disease. Also during eruptions, the joints often become hot, red, swollen, painful and tender. This occurs because the tissue lining of the joint (synovial) becomes inflamed, leading to excessive production of joint fluid (synovial fluid). Synovial also thickens with inflammation (synovitis).
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